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Cryoptococcal meningitis
January 2007 View PDF En
español
Do the drugs cause any serious side effects?
Nearly all prescribed medication can cause at least some minor
side effects in some people. Some side effects can be eliminated
or treated. The chart below describes the most common side effects
associated with the drugs used to treat cryptococcal meningitis.
| Drug
Name |
|
|
Side
Effects |
|
Notes |
| Amphotericin
B
(Fungizone)
or
Liposomal AmB
(Amphotec, Ambisome, Abelcet) |
|
|
Mild-to-Moderate:
Fever, chills, nausea, vomiting, diarrhea, headache and muscle
pains
Severe: Immediate and severe allergic reaction,
kidney toxicity, anemia |
|
Acetaminophen*
(Tylenol) and diphenhydramine (IV Benadryl) given one half
hour before taking Amphotericin B can reduce minor side effects.
Amphotericin B should be given only with extreme caution to
people with kidney problems. |
| Flucytosine
(Ancobon) |
|
|
Mild-to-Moderate:
Nausea, headache, skin rash, vomiting, abdominal pain, diarrhea,
increased triglycerides |
|
Dosage
reduction necessary in people with kidney problems. May cause
birth defects if used in pregnant women. |
| Fluconazole
(Diflucan) |
|
|
Mild-to-Moderate:
Nausea, headache, skin rash, vomiting, abdominal pain, diarrhea,
increased triglycerides |
|
Pregnant
women are advised not to use fluconazole or any of the ‘azole’
drugs during pregnancy, as they may lead to severe birth defects.
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* Acetaminophen (Tylenol) can be toxic to the liver and other alternatives
are available like ibuprofen (Advil) and Naproxen (Aleve)
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© 2009 Project Inform 1375
Mission Street, San Francisco, CA 94103 415-558-8669
National HIV/AIDS Treatment Hotline 1-800-822-7422 (415-558-9051 local/int'l) 10a-4p Mon-Fri PST
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