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Systemic candidiasis

January 2005     View PDF     En español

Candidiasis chart

 

TYPE

 

SYMPTOMS

 

DIAGNOSIS

 

TREATMENT

 

PREVENTION

 

Oral (thrush), affects mouth and throat; usually occurs at CD4+ cell counts below 300

 

Discomfort, burning of mouth and throat; changed sense of taste; creamy white or yellowish patches on mouth or throat.

 

By appearance and symptoms. Lab tests are used if the infection does not clear after treatment.

 

Mouth rinses (nystatin, Mycostatin). Lozenges (nystatin, Mycostatin; clotrimazole, Mycelex). Capsules (fluconazole, Diflucan 100mg/day or itraconazole, Sporanox 200mg/day)

 

Maintain good oral/dental hygiene. Avoid smoking and excess sugar.

Weekly fluconazole.

 

Vaginal (vaginitis, yeast infection), affects vagina and/or vulva

 

Odorous, white-yellow, creamy discharge with burning, swelling and itching.

 

By appearance and symptoms. Lab tests are used if the infection does not clear after treatment.

 

Vaginal creams or suppositories (clotrimazole or miconazole). Fluconazole oral tablets.

 

Avoid douching and scented laundry soap, bleach and fabric softeners. Avoid washing vaginal area with deodorant soaps.

Wear loose fitting clothing and cotton underwear.

Weekly fluconazole.

 

Esophageal, affects the esophagus (feeding tube); usually occurs at CD4+ cell counts below 100

 

Chest pain, nausea and painful swallowing.

Usually occurs with oral candidiasis.

 

Examination of oropharnyx; endoscopy; culture and histology.

 

Ketoconazole (Nizoral) 200 or 400mg/day or Fluconazole Diflucan) at 200mg once a day.

 

If more than one case has occurred, fluconazole preventive therapy may be warranted, particularly at low CD4+ cell counts.

 

Skin (usually affects skin in armpits, groin and under breasts)

 

Bright red, uneven eruption in the folds of skin that may be coated with a white membrane; mild burning feeling.

 

By appearance and symptoms. Lab tests are used if the infection does not clear after treatment.

 

Creams or ointments applied 2–4 times/day. Products include clotrimazole nystatin, ketoconazole, miconazole, econazole and amphotericin B.

 

Keep skin dry.

 

Systemic (affects organs throughout the body)

 

 

 

Can be difficult to diagnose.

 

Amphotericin B (Fungizone) orally or intravenously.

 

 

 
     
 

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