Project Inform
   

Oral candidiasis (thrush)

November 2005     View PDF     En español

Treating oral candidiasis

 

Drug Name

 

Dose

 

Side effects

 

Notes

TOPICAL THERAPIES

 

Clotrimazole
(Mycelex) troches

 

10mg 4–5 times daily for 1–2 weeks

 

May cause altered taste and stomach upset

 

Suck slowly; do not chew or swallow whole

 

Nystatin
(Mycostatin) Pastille

 

1–2 pastilles
4–5 times daily

 

May cause irritation in the mouth; nausea

 

Suck slowly; do not chew or swallow whole

 

Nystatin
(Mycostatin) oral suspension

 

5ml four times daily for 7–14 days

 

May cause stomach upset

 

Swish around mouth before swallowing

TOPICAL THERAPIES

 

Ketoconazole
(Nizoral) tablet

 

200mg a day, 7–14 days; 400mg day, 14–21 days*

 

Nausea, vomiting, stomach pain; liver toxicity

 

Monitor liver function while taking this drug; Take with food

 

Itraconazole
(Sporanox)

 

100mg a day, 7–14 days; 200mg a day, 14–21 days*

 

Nausea, vomiting, stomach pain; liver toxicity

 

Monitor liver function while taking this drug

 

Fluconazole
(Diflucan)

 

200mg a day, 7–14 days; 200mg a day, 14–21 days*

 

Nausea, vomiting, stomach pain; liver toxicity

 

Monitor liver function while taking this drug

 

Amphotericin B (Fungizone)
Amphotericin B lipid complex (Abelcet)

 

100mg a day four times daily (oral suspension);
0.5mg/kg a day, 14–21 days (intravenous)*

 

For intravenous form: kidney toxicity, electrolyte losses, fever, chills, sweats

 

For oral suspension, swish around mouth before swallowing; monitor kidney function

OTHER THERAPIES

 

Gentian violet
(1% solution in water)

 

Applied to affected areas twice a day for three days

 

May cause swelling

 

Available over-the-counter. May be useful for recurrent infections when applied every 7 days for 1 month; messy application.

  *Esophageal candidiasis

 

 
     
 

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